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MERKEL CELL CARCINOMA

This is a very rare tumor commonly seen on the head and neck.  It occurs mostly in the elderly.

It is seen as purplish papules and nodules on the head and neck.

Initially thought to be a tumor in the sweat glands, it is established that it is tumor of a specialized type called Merkel cell.  This helps to transmit touch sensations in the skin.

Removing the tumor by a skin biopsy is the best treatment.

In addition radiation treatment to the area as with removal of the lymphnodes is an accepted treatment modality.

Other treatments tried include

1. Cyclophosphamide
2. Doxorubicin

3.   Vincristine                         

 all the above are  anti cancer drugs

Latest treatment

Intra tumor injections of recombinant human tumor necrosis factor.